TOP2B - RYR1

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
TOP2B	ENSG00000077097	No diseases in record	ETOPOSIDE TENIPOSIDE	chromatin binding DNA topoisomerase type II (ATP-hydrolyzing) activity protein kinase C binding ATP binding protein C-terminus binding DNA binding, bending enzyme binding histone deacetylase binding metal ion binding protein heterodimerization activity	TOP2 (S. cerevisiae) cin-4 (C. elegans) top-2 (C. elegans)
RYR1	ENSG00000196218	No diseases in record	DANTROLENE	protease binding ryanodine-sensitive calcium-release channel activity voltage-gated calcium channel activity calcium channel activity calcium ion binding protein binding calmodulin binding calcium-release channel activity calcium-induced calcium release activity	RyR (D. melanogaster)