TOP2B - MECOM

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
TOP2B	ENSG00000077097	No diseases in record	ETOPOSIDE TENIPOSIDE	chromatin binding DNA topoisomerase type II (ATP-hydrolyzing) activity protein kinase C binding ATP binding protein C-terminus binding DNA binding, bending enzyme binding histone deacetylase binding metal ion binding protein heterodimerization activity	TOP2 (S. cerevisiae) cin-4 (C. elegans) top-2 (C. elegans)
MECOM	ENSG00000085276	AML CML MDS	No drugs in record	DNA binding transcription factor activity, sequence-specific DNA binding protein binding histone-lysine N-methyltransferase activity metal ion binding	COM2 (S. cerevisiae) MSN2 (S. cerevisiae)