MAP2K4 - SRC

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
MAP2K4	ENSG00000065559	pancreatic breast colorectal	No drugs in record	protein kinase activity signal transducer, downstream of receptor, with serine/threonine kinase activity protein tyrosine kinase activity protein binding ATP binding JUN kinase kinase activity mitogen-activated protein kinase kinase kinase binding	PBS2 (S. cerevisiae) sek-3 (C. elegans) mkk-4 (C. elegans) sek-6 (C. elegans) Mkk4 (D. melanogaster)
SRC	ENSG00000197122	colorectal cancer endometrial carcinoma	BOSUTINIB DASATINIB VANDETANIB	protein kinase activity protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity SH3/SH2 adaptor activity protein kinase C binding receptor binding insulin receptor binding integrin binding protein binding ATP binding protein C-terminus binding kinase activity enzyme binding kinase binding heme binding estrogen receptor binding SH2 domain binding ion channel binding ephrin receptor binding phosphoprotein binding hormone receptor binding growth factor receptor binding scaffold protein binding cadherin binding involved in cell-cell adhesion	Src64B (D. melanogaster)