HSP90AB1 - EGFR

H. sapiens

SDL interaction

Identifiers

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
HSP90AB1	ENSG00000096384	NHL	No drugs in record	glycoprotein binding UTP binding CTP binding double-stranded RNA binding protein binding ATP binding GTP binding drug binding sulfonylurea receptor binding protein kinase regulator activity kinase binding protein kinase binding MHC class II protein complex binding nitric-oxide synthase regulator activity TPR domain binding heat shock protein binding dATP binding histone deacetylase binding ion channel binding protein dimerization activity unfolded protein binding cadherin binding involved in cell-cell adhesion histone methyltransferase binding	HSC82 (S. cerevisiae) HSP82 (S. cerevisiae) daf-21 (C. elegans) Hsp83 (D. melanogaster)
EGFR	ENSG00000146648	glioma NSCLC	AFATINIB CETUXIMAB ERLOTINIB GEFITINIB LAPATINIB PANITUMUMAB VANDETANIB	glycoprotein binding chromatin binding double-stranded DNA binding MAP kinase kinase kinase activity protein tyrosine kinase activity transmembrane receptor protein tyrosine kinase activity signal transducer, downstream of receptor, with protein tyrosine kinase activity transmembrane signaling receptor activity epidermal growth factor-activated receptor activity Ras guanyl-nucleotide exchange factor activity integrin binding protein binding calmodulin binding ATP binding enzyme binding protein kinase binding protein phosphatase binding ubiquitin protein ligase binding identical protein binding phosphatidylinositol-4,5-bisphosphate 3-kinase activity protein heterodimerization activity epidermal growth factor binding actin filament binding cadherin binding involved in cell-cell adhesion nitric-oxide synthase regulator activity protein domain specific binding	let-23 (C. elegans) Egfr (D. melanogaster)