AXIN1 - IQGAP1

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
AXIN1	ENSG00000103126	colorectal endometrial prostate hepatocellular carcinoma hepatoblastoma sporadic medulloblastoma	No drugs in record	signal transducer activity GTPase activator activity protein binding beta-catenin binding enzyme binding protein kinase binding receptor signaling complex scaffold activity ubiquitin protein ligase binding protein complex scaffold activity identical protein binding protein homodimerization activity SMAD binding armadillo repeat domain binding I-SMAD binding	Axn (D. melanogaster)
IQGAP1	ENSG00000140575	No diseases in record	No drugs in record	GTPase inhibitor activity GTPase activator activity calcium ion binding protein binding calmodulin binding phosphatidylinositol-3,4,5-trisphosphate binding protein kinase binding protein phosphatase binding protein domain specific binding protein complex binding protein serine/threonine kinase activator activity S100 protein binding Rac GTPase binding mitogen-activated protein kinase binding cadherin binding involved in cell-cell adhesion	IQG1 (S. cerevisiae)