TOP2B - IQGAP1

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
TOP2B	ENSG00000077097	No diseases in record	ETOPOSIDE TENIPOSIDE	chromatin binding DNA topoisomerase type II (ATP-hydrolyzing) activity protein kinase C binding ATP binding protein C-terminus binding DNA binding, bending enzyme binding histone deacetylase binding metal ion binding protein heterodimerization activity	TOP2 (S. cerevisiae) cin-4 (C. elegans) top-2 (C. elegans)
IQGAP1	ENSG00000140575	No diseases in record	No drugs in record	GTPase inhibitor activity GTPase activator activity calcium ion binding protein binding calmodulin binding phosphatidylinositol-3,4,5-trisphosphate binding protein kinase binding protein phosphatase binding protein domain specific binding protein complex binding protein serine/threonine kinase activator activity S100 protein binding Rac GTPase binding mitogen-activated protein kinase binding cadherin binding involved in cell-cell adhesion	IQG1 (S. cerevisiae)