KAT2A - WRN

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
KAT2A	ENSG00000108773	No diseases in record	No drugs in record	chromatin binding transcription coactivator activity histone acetyltransferase activity protein binding transcription factor binding H3 histone acetyltransferase activity protein phosphatase binding histone deacetylase binding histone acetyltransferase activity (H4-K12 specific)	GCN5 (S. cerevisiae) pcaf-1 (C. elegans) Gcn5 (D. melanogaster)
WRN	ENSG00000165392	osteosarcoma meningioma other tumour types	No drugs in record	magnesium ion binding Y-form DNA binding bubble DNA binding DNA binding DNA helicase activity chromatin binding ATP-dependent DNA helicase activity helicase activity exonuclease activity protein binding ATP binding 3'-5' exonuclease activity four-way junction helicase activity ATPase activity manganese ion binding protein complex binding protein homodimerization activity 3'-5' DNA helicase activity ATP-dependent 3'-5' DNA helicase activity G-quadruplex DNA binding	SGS1 (S. cerevisiae) wrn-1 (C. elegans)