MET - NOTCH1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
MET	ENSG00000105976	papillary renal head-neck squamous cell	CABOZANTINIB CRIZOTINIB	protein tyrosine kinase activity hepatocyte growth factor-activated receptor activity protein binding ATP binding protein phosphatase binding juvenile hormone binding protein homodimerization activity protein heterodimerization activity transcription factor binding juvenile hormone receptor activity	F11E6.8 (C. elegans)
NOTCH1	ENSG00000148400	T-ALL breast bladder skin SCC lung SCC head and neck SCC	No drugs in record	core promoter binding transcriptional activator activity, RNA polymerase II transcription factor binding transcription factor activity, sequence-specific DNA binding enzyme inhibitor activity receptor activity Notch binding calcium ion binding protein binding enzyme binding chromatin DNA binding sequence-specific DNA binding protein heterodimerization activity	N (D. melanogaster)