POLD1 - MCM4

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
POLD1	ENSG00000062822	CRC	CLOFARABINE CYTARABINE FLUDARABINE PHOSPHATE GEMCITABINE	nucleotide binding DNA binding chromatin binding damaged DNA binding DNA-directed DNA polymerase activity protein binding 3'-5'-exodeoxyribonuclease activity enzyme binding metal ion binding 4 iron, 4 sulfur cluster binding	POL3 (S. cerevisiae) F10C2.4 (C. elegans) DNApol-delta (D. melanogaster)
MCM4	ENSG00000104738	No diseases in record	No drugs in record	single-stranded DNA binding protein binding ATP binding ATP-dependent DNA helicase activity single-stranded DNA-dependent ATP-dependent DNA helicase activity ATP-dependent four-way junction helicase activity DNA replication origin binding DNA binding helicase activity ATP-dependent 3'-5' DNA helicase activity DNA helicase activity nucleotide binding single-stranded DNA-dependent ATPase activity hydrolase activity single-stranded RNA binding 3'-5' DNA/RNA helicase activity ATPase activity single-stranded DNA-dependent ATP-dependent 3'-5' DNA helicase activity RNA helicase activity chromatin binding	MCM4 (S. cerevisiae) dpa (D. melanogaster)