INO80 - POLE

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
INO80	ENSG00000128908	No diseases in record	No drugs in record	DNA binding DNA helicase activity actin binding protein binding ATP binding ATPase activity alpha-tubulin binding helicase activity hydrolase activity nucleotide binding ATP-dependent 3'-5' DNA helicase activity regulatory region DNA binding	INO80 (S. cerevisiae) Ino80 (D. melanogaster)
POLE	ENSG00000177084	colorectal carcinoma endometrioid carcinoma stomach carcinoma skin cancer colorectal cancer susceptibility	CLOFARABINE CYTARABINE FLUDARABINE PHOSPHATE GEMCITABINE	nucleotide binding DNA binding chromatin binding DNA-directed DNA polymerase activity zinc ion binding single-stranded DNA 3'-5' exodeoxyribonuclease activity 4 iron, 4 sulfur cluster binding	POL2 (S. cerevisiae) pole-1 (C. elegans) DNApol-epsilon255 (D. melanogaster)