PDGFRB - NCOA2

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
PDGFRB	ENSG00000113721	MPN AML CMML CML	BECAPLERMIN DASATINIB IMATINIB NINTEDANIB PAZOPANIB REGORAFENIB SORAFENIB SUNITINIB	protein tyrosine kinase activity platelet activating factor receptor activity platelet-derived growth factor-activated receptor activity platelet-derived growth factor beta-receptor activity Ras guanyl-nucleotide exchange factor activity receptor binding platelet-derived growth factor receptor binding protein binding ATP binding enzyme binding protein kinase binding vascular endothelial growth factor binding phosphatidylinositol 3-kinase binding phosphatidylinositol-4,5-bisphosphate 3-kinase activity platelet-derived growth factor binding	Pvr (D. melanogaster)
NCOA2	ENSG00000140396	AML chondrosarcoma rhabdomyosarcoma	No drugs in record	RNA polymerase II core promoter proximal region sequence-specific DNA binding RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding chromatin binding transcription coactivator activity histone acetyltransferase activity protein binding transcription factor binding ligand-dependent nuclear receptor binding ligand-dependent nuclear receptor transcription coactivator activity thyroid hormone receptor coactivator activity nuclear hormone receptor binding protein dimerization activity	No GO terms in record