PDGFRB - HMGA1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
PDGFRB	ENSG00000113721	MPN AML CMML CML	BECAPLERMIN DASATINIB IMATINIB NINTEDANIB PAZOPANIB REGORAFENIB SORAFENIB SUNITINIB	protein tyrosine kinase activity platelet activating factor receptor activity platelet-derived growth factor-activated receptor activity platelet-derived growth factor beta-receptor activity Ras guanyl-nucleotide exchange factor activity receptor binding platelet-derived growth factor receptor binding protein binding ATP binding enzyme binding protein kinase binding vascular endothelial growth factor binding phosphatidylinositol 3-kinase binding phosphatidylinositol-4,5-bisphosphate 3-kinase activity platelet-derived growth factor binding	Pvr (D. melanogaster)
HMGA1	ENSG00000137309	microfollicular thyroid adenoma various benign mesenchymal tumours	No drugs in record	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding DNA binding AT DNA binding chromatin binding transcription factor activity, sequence-specific DNA binding protein binding transcription factor binding enzyme binding ligand-dependent nuclear receptor transcription coactivator activity retinoic acid receptor binding peroxisome proliferator activated receptor binding retinoid X receptor binding	No GO terms in record