SKP1 - KDR

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
SKP1	ENSG00000113558	No diseases in record	No drugs in record	ubiquitin-protein transferase activity protein binding beta-catenin binding cullin family protein binding ubiquitin protein ligase activity DNA replication origin binding DNA binding	SKP1 (S. cerevisiae) skr-2 (C. elegans) skr-1 (C. elegans) skr-17 (C. elegans) skr-9 (C. elegans) skr-8 (C. elegans) skr-7 (C. elegans) skr-18 (C. elegans) skr-10 (C. elegans) skr-13 (C. elegans) skr-12 (C. elegans) SkpA (D. melanogaster) SkpE (D. melanogaster) SkpB (D. melanogaster) SkpF (D. melanogaster) SkpC (D. melanogaster) SkpD (D. melanogaster)
KDR	ENSG00000128052	NSCLC angiosarcoma melanoma	AXITINIB CABOZANTINIB LENVATINIB NINTEDANIB PAZOPANIB PONATINIB RAMUCIRUMAB REGORAFENIB SORAFENIB SUNITINIB VANDETANIB	protein tyrosine kinase activity transmembrane receptor protein tyrosine kinase activity signal transducer, downstream of receptor, with protein tyrosine kinase activity vascular endothelial growth factor-activated receptor activity integrin binding protein binding ATP binding growth factor binding Hsp90 protein binding	Pvr (D. melanogaster)