PDGFRB - THRA

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
PDGFRB	ENSG00000113721	MPN AML CMML CML	BECAPLERMIN DASATINIB IMATINIB NINTEDANIB PAZOPANIB REGORAFENIB SORAFENIB SUNITINIB	protein tyrosine kinase activity platelet activating factor receptor activity platelet-derived growth factor-activated receptor activity platelet-derived growth factor beta-receptor activity Ras guanyl-nucleotide exchange factor activity receptor binding platelet-derived growth factor receptor binding protein binding ATP binding enzyme binding protein kinase binding vascular endothelial growth factor binding phosphatidylinositol 3-kinase binding phosphatidylinositol-4,5-bisphosphate 3-kinase activity platelet-derived growth factor binding	Pvr (D. melanogaster)
THRA	ENSG00000126351	No diseases in record	DEXTROTHYROXINE LEVOTHYROXINE LIOTHYRONINE	transcription regulatory region sequence-specific DNA binding steroid receptor RNA activator RNA binding transcription factor activity, sequence-specific DNA binding steroid hormone receptor activity thyroid hormone receptor activity protein binding transcription factor binding zinc ion binding TBP-class protein binding protein domain specific binding chromatin DNA binding protein complex binding transcription regulatory region DNA binding thyroid hormone binding	EcR (D. melanogaster)