PDGFRB - AXIN2

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
PDGFRB	ENSG00000113721	MPN AML CMML CML	BECAPLERMIN DASATINIB IMATINIB NINTEDANIB PAZOPANIB REGORAFENIB SORAFENIB SUNITINIB	protein tyrosine kinase activity platelet activating factor receptor activity platelet-derived growth factor-activated receptor activity platelet-derived growth factor beta-receptor activity Ras guanyl-nucleotide exchange factor activity receptor binding platelet-derived growth factor receptor binding protein binding ATP binding enzyme binding protein kinase binding vascular endothelial growth factor binding phosphatidylinositol 3-kinase binding phosphatidylinositol-4,5-bisphosphate 3-kinase activity platelet-derived growth factor binding	Pvr (D. melanogaster)
AXIN2	ENSG00000168646	colorectal carcinoma stomach carcinoma hepatocellular carcinoma	No drugs in record	GTPase activator activity protein binding beta-catenin binding enzyme binding protein kinase binding ubiquitin protein ligase binding armadillo repeat domain binding I-SMAD binding	Axn (D. melanogaster)