IRS1 - LCK

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
IRS1	ENSG00000169047	No diseases in record	No drugs in record	signal transducer activity transmembrane receptor protein tyrosine kinase adaptor activity protein kinase C binding Ras guanyl-nucleotide exchange factor activity insulin receptor binding insulin-like growth factor receptor binding protein binding 1-phosphatidylinositol-3-kinase activity SH2 domain binding phosphatidylinositol 3-kinase binding phosphatidylinositol-4,5-bisphosphate 3-kinase activity tRNA binding aminoacyl-tRNA editing activity ATP binding isoleucine-tRNA ligase activity	chico (D. melanogaster)
LCK	ENSG00000182866	T-ALL	DASATINIB PAZOPANIB	glycoprotein binding protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity protein serine/threonine phosphatase activity protein binding ATP binding protein C-terminus binding kinase activity protein kinase binding protein phosphatase binding SH2 domain binding CD4 receptor binding CD8 receptor binding identical protein binding phosphatidylinositol 3-kinase binding phosphatidylinositol-4,5-bisphosphate 3-kinase activity ATPase binding	Src64B (D. melanogaster)