VDR - SMAD2

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
VDR	ENSG00000111424	No diseases in record	CALCIFEDIOL CALCIPOTRIENE CALCITRIOL CHOLECALCIFEROL DOXERCALCIFEROL ERGOCALCIFEROL PARICALCITOL	DNA binding steroid hormone receptor activity protein binding zinc ion binding calcitriol receptor activity lithocholic acid receptor activity sequence-specific DNA binding retinoid X receptor binding calcitriol binding lithocholic acid binding transcription factor activity, sequence-specific DNA binding vitamin D response element binding	EcR (D. melanogaster)
SMAD2	ENSG00000175387	colorectal carcinoma hepatocellular carcinoma	No drugs in record	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding chromatin binding double-stranded DNA binding transcription factor activity, sequence-specific DNA binding transforming growth factor beta receptor binding protein binding transcription factor binding phosphatase binding transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity ubiquitin protein ligase binding activating transcription factor binding type I transforming growth factor beta receptor binding enhancer binding protein homodimerization activity SMAD binding metal ion binding protein heterodimerization activity co-SMAD binding I-SMAD binding R-SMAD binding DNA binding	sma-3 (C. elegans) sma-2 (C. elegans)