EIF2AK2 - POLE

H. sapiens

SSL interaction

Identifiers

Gene Name Gene ID Diseases Drugs GO terms Orthologs
EIF2AK2 ENSG00000055332

No diseases in record

No drugs in record

double-stranded RNA binding
protein kinase activity
protein serine/threonine kinase activity
eukaryotic translation initiation factor 2alpha kinase activity
non-membrane spanning protein tyrosine kinase activity
protein binding
ATP binding
protein phosphatase regulator activity
GCN2 (S. cerevisiae)
POLE ENSG00000177084 colorectal carcinoma
endometrioid carcinoma
stomach carcinoma
skin cancer
colorectal cancer susceptibility
CLOFARABINE
CYTARABINE
FLUDARABINE PHOSPHATE
GEMCITABINE
nucleotide binding
DNA binding
chromatin binding
DNA-directed DNA polymerase activity
zinc ion binding
single-stranded DNA 3'-5' exodeoxyribonuclease activity
4 iron, 4 sulfur cluster binding
POL2 (S. cerevisiae)
pole-1 (C. elegans)
DNApol-epsilon255 (D. melanogaster)