NEDD4L - POLE

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
NEDD4L	ENSG00000049759	No diseases in record	No drugs in record	ubiquitin-protein transferase activity protein binding potassium channel regulator activity sodium channel regulator activity potassium channel inhibitor activity sodium channel inhibitor activity ion channel binding	RSP5 (S. cerevisiae) Nedd4 (D. melanogaster)
POLE	ENSG00000177084	colorectal carcinoma endometrioid carcinoma stomach carcinoma skin cancer colorectal cancer susceptibility	CLOFARABINE CYTARABINE FLUDARABINE PHOSPHATE GEMCITABINE	nucleotide binding DNA binding chromatin binding DNA-directed DNA polymerase activity zinc ion binding single-stranded DNA 3'-5' exodeoxyribonuclease activity 4 iron, 4 sulfur cluster binding	POL2 (S. cerevisiae) pole-1 (C. elegans) DNApol-epsilon255 (D. melanogaster)