MLH1 - TOP2B

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
MLH1	ENSG00000076242	colorectal endometrial ovarian CNS tumours CNS	No drugs in record	chromatin binding protein binding ATP binding ATPase activity guanine/thymine mispair binding single-stranded DNA binding MutSalpha complex binding mismatched DNA binding heteroduplex DNA loop binding DNA insertion or deletion binding dinucleotide insertion or deletion binding double-stranded DNA binding DNA binding	MLH1 (S. cerevisiae) Mlh1 (D. melanogaster)
TOP2B	ENSG00000077097	No diseases in record	ETOPOSIDE TENIPOSIDE	chromatin binding DNA topoisomerase type II (ATP-hydrolyzing) activity protein kinase C binding ATP binding protein C-terminus binding DNA binding, bending enzyme binding histone deacetylase binding metal ion binding protein heterodimerization activity	TOP2 (S. cerevisiae) cin-4 (C. elegans) top-2 (C. elegans)