SMG1 - SKI

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
SMG1	ENSG00000157106	No diseases in record	No drugs in record	protein kinase activity protein serine/threonine kinase activity protein binding ATP binding telomeric DNA binding metal ion binding molecular_function	TOR1 (S. cerevisiae) smg-1 (C. elegans) nonC (D. melanogaster)
SKI	ENSG00000157933	melanoma	No drugs in record	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding chromatin binding transcription corepressor activity protein binding zinc ion binding protein kinase binding protein domain specific binding ubiquitin protein ligase binding SMAD binding histone deacetylase inhibitor activity repressing transcription factor binding	Snoo (D. melanogaster)