ABL1 - DAB2IP

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
ABL1	ENSG00000097007	CML ALL T-ALL	BOSUTINIB DASATINIB IMATINIB NILOTINIB PONATINIB REGORAFENIB	magnesium ion binding DNA binding actin monomer binding nicotinate-nucleotide adenylyltransferase activity protein kinase activity protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity protein kinase C binding protein binding ATP binding protein C-terminus binding SH3 domain binding syntaxin binding manganese ion binding actin filament binding mitogen-activated protein kinase binding proline-rich region binding receptor binding	abl-1 (C. elegans) Abl (D. melanogaster)
DAB2IP	ENSG00000136848	No diseases in record	No drugs in record	GTPase activator activity death receptor binding protein binding SH3 domain binding kinase binding protein kinase binding mitogen-activated protein kinase kinase binding mitogen-activated protein kinase kinase kinase binding phosphatidylinositol-3-phosphate binding protein complex binding signaling adaptor activity phosphatidylinositol 3-kinase regulatory subunit binding identical protein binding protein homodimerization activity vascular endothelial growth factor receptor 2 binding phosphatidylinositol 3-kinase binding protein phosphatase 2A binding phosphatidylinositol-4-phosphate binding 14-3-3 protein binding cadherin binding involved in cell-cell adhesion Toll-like receptor 4 binding	BUD2 (S. cerevisiae) gap-2 (C. elegans) CG42684 (D. melanogaster)