JAK2 - SMG5

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
JAK2	ENSG00000096968	ALL AML MPN CML	RUXOLITINIB TOFACITINIB	protein kinase activity protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity Ras guanyl-nucleotide exchange factor activity receptor binding growth hormone receptor binding interleukin-12 receptor binding protein binding ATP binding protein C-terminus binding protein kinase binding heme binding type 1 angiotensin receptor binding acetylcholine receptor binding histone kinase activity (H3-Y41 specific) SH2 domain binding histone binding phosphatidylinositol 3-kinase binding insulin receptor substrate binding metal ion binding peptide hormone receptor binding	hop (D. melanogaster)
SMG5	ENSG00000198952	No diseases in record	No drugs in record	ribonuclease activity protein binding ubiquitin protein ligase binding telomeric DNA binding histone deacetylase binding ribonucleoprotein complex binding protein phosphatase 2A binding telomerase RNA binding DNA polymerase binding	Smg5 (D. melanogaster)