REV3L - SMAD1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
REV3L	ENSG00000009413	No diseases in record	No drugs in record	nucleotide binding DNA binding DNA-directed DNA polymerase activity protein binding 3'-5' exonuclease activity metal ion binding 4 iron, 4 sulfur cluster binding	REV3 (S. cerevisiae) mus205 (D. melanogaster)
SMAD1	ENSG00000170365	No diseases in record	No drugs in record	RNA polymerase II core promoter proximal region sequence-specific DNA binding RNA polymerase II core promoter sequence-specific DNA binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding transcription factor activity, sequence-specific DNA binding signal transducer activity, downstream of receptor protein binding protein kinase binding transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity identical protein binding protein homodimerization activity metal ion binding protein heterodimerization activity co-SMAD binding I-SMAD binding primary miRNA binding	sma-3 (C. elegans) sma-2 (C. elegans)