INO80 - PTPN11

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
INO80	ENSG00000128908	No diseases in record	No drugs in record	DNA binding DNA helicase activity actin binding protein binding ATP binding ATPase activity alpha-tubulin binding helicase activity hydrolase activity nucleotide binding ATP-dependent 3'-5' DNA helicase activity regulatory region DNA binding	INO80 (S. cerevisiae) Ino80 (D. melanogaster)
PTPN11	ENSG00000179295	JMML AML MDS	No drugs in record	phosphoprotein phosphatase activity protein tyrosine phosphatase activity non-membrane spanning protein tyrosine phosphatase activity SH3/SH2 adaptor activity insulin receptor binding protein binding 1-phosphatidylinositol-3-kinase activity protein domain specific binding receptor tyrosine kinase binding D1 dopamine receptor binding phospholipase binding insulin receptor substrate binding phosphatidylinositol-4,5-bisphosphate 3-kinase activity cell adhesion molecule binding peptide hormone receptor binding	PTP1 (S. cerevisiae) ptp-2 (C. elegans) csw (D. melanogaster)