EIF4G1 - POLE

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
EIF4G1	ENSG00000114867	No diseases in record	No drugs in record	translation initiation factor activity protein binding translation factor activity, RNA binding eukaryotic initiation factor 4E binding cadherin binding involved in cell-cell adhesion	TIF4631 (S. cerevisiae) TIF4632 (S. cerevisiae) ifg-1 (C. elegans) eIF4G2 (D. melanogaster)
POLE	ENSG00000177084	colorectal carcinoma endometrioid carcinoma stomach carcinoma skin cancer colorectal cancer susceptibility	CLOFARABINE CYTARABINE FLUDARABINE PHOSPHATE GEMCITABINE	nucleotide binding DNA binding chromatin binding DNA-directed DNA polymerase activity zinc ion binding single-stranded DNA 3'-5' exodeoxyribonuclease activity 4 iron, 4 sulfur cluster binding	POL2 (S. cerevisiae) pole-1 (C. elegans) DNApol-epsilon255 (D. melanogaster)