PIAS1 - PDGFRB

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
PIAS1	ENSG00000033800	No diseases in record	No drugs in record	DNA binding transcription coactivator activity transcription corepressor activity protein binding protein C-terminus binding transcription factor binding zinc ion binding ligase activity SUMO transferase activity enzyme binding protein domain specific binding ubiquitin protein ligase binding androgen receptor binding SUMO ligase activity	NFI1 (S. cerevisiae) SIZ1 (S. cerevisiae) gei-17 (C. elegans) Su(var)2-10 (D. melanogaster)
PDGFRB	ENSG00000113721	MPN AML CMML CML	BECAPLERMIN DASATINIB IMATINIB NINTEDANIB PAZOPANIB REGORAFENIB SORAFENIB SUNITINIB	protein tyrosine kinase activity platelet activating factor receptor activity platelet-derived growth factor-activated receptor activity platelet-derived growth factor beta-receptor activity Ras guanyl-nucleotide exchange factor activity receptor binding platelet-derived growth factor receptor binding protein binding ATP binding enzyme binding protein kinase binding vascular endothelial growth factor binding phosphatidylinositol 3-kinase binding phosphatidylinositol-4,5-bisphosphate 3-kinase activity platelet-derived growth factor binding	Pvr (D. melanogaster)