TBP - TERT

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
TBP	ENSG00000112592	No diseases in record	No drugs in record	RNA polymerase II core promoter proximal region sequence-specific DNA binding RNA polymerase II core promoter sequence-specific DNA binding RNA polymerase III transcription factor activity, sequence-specific DNA binding RNA polymerase II repressing transcription factor binding protein binding transcription factor binding enzyme binding transcription regulatory region DNA binding repressing transcription factor binding transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly TFIIA-class transcription factor binding RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly core promoter binding chromatin binding	SPT15 (S. cerevisiae) tbp-1 (C. elegans) Tbp (D. melanogaster)
TERT	ENSG00000164362	melanoma glioblastoma hepatocellular carcinoma bladder skin basal cell skin squamous cell mesothelioma medulloblastoma other tumour types	No drugs in record	tRNA binding transcription coactivator binding DNA binding telomerase activity telomerase RNA reverse transcriptase activity RNA binding RNA-directed DNA polymerase activity protein binding nucleotidyltransferase activity telomeric DNA binding protein homodimerization activity metal ion binding telomerase RNA binding RNA-directed 5'-3' RNA polymerase activity	EST2 (S. cerevisiae)