POLD1 - SDHB

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
POLD1	ENSG00000062822	CRC	CLOFARABINE CYTARABINE FLUDARABINE PHOSPHATE GEMCITABINE	nucleotide binding DNA binding chromatin binding damaged DNA binding DNA-directed DNA polymerase activity protein binding 3'-5'-exodeoxyribonuclease activity enzyme binding metal ion binding 4 iron, 4 sulfur cluster binding	POL3 (S. cerevisiae) F10C2.4 (C. elegans) DNApol-delta (D. melanogaster)
SDHB	ENSG00000117118	paraganglioma pheochromocytoma	No drugs in record	succinate dehydrogenase activity protein binding succinate dehydrogenase (ubiquinone) activity electron carrier activity metal ion binding ubiquinone binding 2 iron, 2 sulfur cluster binding 3 iron, 4 sulfur cluster binding 4 iron, 4 sulfur cluster binding	SDH2 (S. cerevisiae) sdhb-1 (C. elegans) SdhB (D. melanogaster)