VDR - TOP2A

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
VDR	ENSG00000111424	No diseases in record	CALCIFEDIOL CALCIPOTRIENE CALCITRIOL CHOLECALCIFEROL DOXERCALCIFEROL ERGOCALCIFEROL PARICALCITOL	DNA binding steroid hormone receptor activity protein binding zinc ion binding calcitriol receptor activity lithocholic acid receptor activity sequence-specific DNA binding retinoid X receptor binding calcitriol binding lithocholic acid binding transcription factor activity, sequence-specific DNA binding vitamin D response element binding	EcR (D. melanogaster)
TOP2A	ENSG00000131747	No diseases in record	DAUNORUBICIN DOXORUBICIN EPIRUBICIN ETOPOSIDE ETOPOSIDE PHOSPHATE IDARUBICIN MITOXANTRONE PODOFILOX TENIPOSIDE VALRUBICIN	magnesium ion binding DNA binding chromatin binding DNA topoisomerase type II (ATP-hydrolyzing) activity protein kinase C binding protein binding ATP binding protein C-terminus binding DNA-dependent ATPase activity drug binding DNA binding, bending enzyme binding protein homodimerization activity histone deacetylase binding ubiquitin binding protein heterodimerization activity	TOP2 (S. cerevisiae) cin-4 (C. elegans) top-2 (C. elegans)