TOP2A - MEN1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
TOP2A	ENSG00000131747	No diseases in record	DAUNORUBICIN DOXORUBICIN EPIRUBICIN ETOPOSIDE ETOPOSIDE PHOSPHATE IDARUBICIN MITOXANTRONE PODOFILOX TENIPOSIDE VALRUBICIN	magnesium ion binding DNA binding chromatin binding DNA topoisomerase type II (ATP-hydrolyzing) activity protein kinase C binding protein binding ATP binding protein C-terminus binding DNA-dependent ATPase activity drug binding DNA binding, bending enzyme binding protein homodimerization activity histone deacetylase binding ubiquitin binding protein heterodimerization activity	TOP2 (S. cerevisiae) cin-4 (C. elegans) top-2 (C. elegans)
MEN1	ENSG00000133895	parathyroid tumours pancreatic neuroendocrine tumour parathyroid adenoma pituitary adenoma pancreatic islet cell carcinoid	No drugs in record	four-way junction DNA binding Y-form DNA binding chromatin binding double-stranded DNA binding protein binding protein binding, bridging transcription regulatory region DNA binding protein N-terminus binding R-SMAD binding histone-lysine N-methyltransferase activity	Mnn1 (D. melanogaster)