MAP3K4 - POLE

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
MAP3K4	ENSG00000085511	No diseases in record	No drugs in record	MAP kinase kinase kinase activity protein binding ATP binding metal ion binding	SSK2 (S. cerevisiae) SSK22 (S. cerevisiae) drl-1 (C. elegans) Mekk1 (D. melanogaster)
POLE	ENSG00000177084	colorectal carcinoma endometrioid carcinoma stomach carcinoma skin cancer colorectal cancer susceptibility	CLOFARABINE CYTARABINE FLUDARABINE PHOSPHATE GEMCITABINE	nucleotide binding DNA binding chromatin binding DNA-directed DNA polymerase activity zinc ion binding single-stranded DNA 3'-5' exodeoxyribonuclease activity 4 iron, 4 sulfur cluster binding	POL2 (S. cerevisiae) pole-1 (C. elegans) DNApol-epsilon255 (D. melanogaster)