MCM4 - SMAD2

H. sapiens

SSL interaction

Identifiers

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
MCM4	ENSG00000104738	No diseases in record	No drugs in record	single-stranded DNA binding protein binding ATP binding ATP-dependent DNA helicase activity single-stranded DNA-dependent ATP-dependent DNA helicase activity ATP-dependent four-way junction helicase activity DNA replication origin binding DNA binding helicase activity ATP-dependent 3'-5' DNA helicase activity DNA helicase activity nucleotide binding single-stranded DNA-dependent ATPase activity hydrolase activity single-stranded RNA binding 3'-5' DNA/RNA helicase activity ATPase activity single-stranded DNA-dependent ATP-dependent 3'-5' DNA helicase activity RNA helicase activity chromatin binding	MCM4 (S. cerevisiae) dpa (D. melanogaster)
SMAD2	ENSG00000175387	colorectal carcinoma hepatocellular carcinoma	No drugs in record	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding chromatin binding double-stranded DNA binding transcription factor activity, sequence-specific DNA binding transforming growth factor beta receptor binding protein binding transcription factor binding phosphatase binding transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity ubiquitin protein ligase binding activating transcription factor binding type I transforming growth factor beta receptor binding enhancer binding protein homodimerization activity SMAD binding metal ion binding protein heterodimerization activity co-SMAD binding I-SMAD binding R-SMAD binding DNA binding	sma-3 (C. elegans) sma-2 (C. elegans)