FGFR3 - NOTCH1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
FGFR3	ENSG00000068078	bladder MM T-cell lymphoma	NINTEDANIB PAZOPANIB	protein tyrosine kinase activity fibroblast growth factor-activated receptor activity Ras guanyl-nucleotide exchange factor activity protein binding ATP binding 1-phosphatidylinositol-3-kinase activity fibroblast growth factor binding phosphatidylinositol-4,5-bisphosphate 3-kinase activity	egl-15 (C. elegans) htl (D. melanogaster)
NOTCH1	ENSG00000148400	T-ALL breast bladder skin SCC lung SCC head and neck SCC	No drugs in record	core promoter binding transcriptional activator activity, RNA polymerase II transcription factor binding transcription factor activity, sequence-specific DNA binding enzyme inhibitor activity receptor activity Notch binding calcium ion binding protein binding enzyme binding chromatin DNA binding sequence-specific DNA binding protein heterodimerization activity	N (D. melanogaster)