E2F1 - DHFR

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
E2F1	ENSG00000101412	No diseases in record	No drugs in record	core promoter binding DNA binding transcription factor activity, sequence-specific DNA binding protein binding transcription factor binding protein kinase binding sequence-specific DNA binding protein dimerization activity RNA polymerase II transcription factor activity, sequence-specific DNA binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding RNA polymerase II regulatory region DNA binding	E2f1 (D. melanogaster)
DHFR	ENSG00000228716	No diseases in record	METHOTREXATE PEMETREXED PRALATREXATE	mRNA binding dihydrofolate reductase activity folic acid binding drug binding folate reductase activity methotrexate binding NADPH binding protein binding NADP binding	DFR1 (S. cerevisiae)