DDX1 - TOP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
DDX1	ENSG00000079785	No diseases in record	No drugs in record	DNA binding chromatin binding transcription cofactor activity RNA helicase activity double-stranded RNA binding ATP-dependent RNA helicase activity nuclease activity exonuclease activity protein binding ATP binding ATP-dependent helicase activity poly(A) binding DNA/RNA helicase activity helicase activity	DBP3 (S. cerevisiae) MSS116 (S. cerevisiae) Y55F3BR.1 (C. elegans) Ddx1 (D. melanogaster)
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)