KIF5B - TOP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
KIF5B	ENSG00000170759	NSCLC Spitzoid tumour	No drugs in record	microtubule motor activity protein binding ATP binding microtubule binding JUN kinase binding ATP-dependent microtubule motor activity, plus-end-directed cadherin binding involved in cell-cell adhesion	KAR3 (S. cerevisiae) Khc (D. melanogaster)
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)