HDAC4 - JAK1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
HDAC4	ENSG00000068024	No diseases in record	BELINOSTAT PANOBINOSTAT ROMIDEPSIN	RNA polymerase III transcription factor binding core promoter binding chromatin binding transcription corepressor activity histone deacetylase activity protein binding transcription factor binding zinc ion binding protein kinase binding potassium ion binding NAD-dependent histone deacetylase activity (H3-K14 specific) protein deacetylase activity activating transcription factor binding histone deacetylase binding repressing transcription factor binding sequence-specific DNA binding transcription regulatory region DNA binding	HDA1 (S. cerevisiae) hda-4 (C. elegans) HDAC4 (D. melanogaster)
JAK1	ENSG00000162434	ALL	RUXOLITINIB TOFACITINIB	protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity Ras guanyl-nucleotide exchange factor activity receptor binding growth hormone receptor binding protein binding ATP binding protein phosphatase binding ubiquitin protein ligase binding CCR5 chemokine receptor binding metal ion binding	hop (D. melanogaster)