FKBP1A - JAK1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
FKBP1A	ENSG00000088832	No diseases in record	CYCLOSPORINE EVEROLIMUS PIMECROLIMUS SIROLIMUS TACROLIMUS TEMSIROLIMUS	peptidyl-prolyl cis-trans isomerase activity signal transducer activity transforming growth factor beta receptor binding protein binding macrolide binding FK506 binding enzyme binding Hsp70 protein binding type I transforming growth factor beta receptor binding protein homodimerization activity ion channel binding SMAD binding activin binding calcium channel inhibitor activity	FPR1 (S. cerevisiae) FK506-bp2 (D. melanogaster)
JAK1	ENSG00000162434	ALL	RUXOLITINIB TOFACITINIB	protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity Ras guanyl-nucleotide exchange factor activity receptor binding growth hormone receptor binding protein binding ATP binding protein phosphatase binding ubiquitin protein ligase binding CCR5 chemokine receptor binding metal ion binding	hop (D. melanogaster)