KCNH2 - BRAF

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
KCNH2	ENSG00000055118	No diseases in record	AMIODARONE DALFAMPRIDINE DOFETILIDE GUANIDINE IBUTILIDE SOTALOL	phosphorelay sensor kinase activity inward rectifier potassium channel activity voltage-gated potassium channel activity delayed rectifier potassium channel activity protein binding ubiquitin protein ligase binding identical protein binding protein homodimerization activity C3HC4-type RING finger domain binding voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization scaffold protein binding voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization	No GO terms in record
BRAF	ENSG00000157764	melanoma colorectal papillary thyroid borderline ovarian NSCLC cholangiocarcinoma pilocytic astrocytoma Spitzoid tumour pancreas acinar carcinoma melanocytic nevus prostate gastric	DABRAFENIB REGORAFENIB SORAFENIB VEMURAFENIB	protein kinase activity protein serine/threonine kinase activity MAP kinase kinase kinase activity calcium ion binding protein binding ATP binding mitogen-activated protein kinase kinase binding identical protein binding protein heterodimerization activity small GTPase binding	lin-45 (C. elegans)