KIT - RET

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
KIT	ENSG00000157404	GIST AML TGCT mastocytosis mucosal melanoma epithelioma	CABOZANTINIB DASATINIB IMATINIB LENVATINIB PAZOPANIB PONATINIB REGORAFENIB SORAFENIB SUNITINIB	protease binding protein tyrosine kinase activity transmembrane receptor protein tyrosine kinase activity signal transducer, downstream of receptor, with protein tyrosine kinase activity stem cell factor receptor activity Ras guanyl-nucleotide exchange factor activity protein binding ATP binding cytokine binding protein homodimerization activity metal ion binding phosphatidylinositol-4,5-bisphosphate 3-kinase activity	Pvr (D. melanogaster)
RET	ENSG00000165731	medullary thyroid papillary thyroid pheochromocytoma NSCLC Spitzoid tumour	CABOZANTINIB LENVATINIB REGORAFENIB SORAFENIB SUNITINIB VANDETANIB	protein tyrosine kinase activity transmembrane receptor protein tyrosine kinase activity receptor activity Ras guanyl-nucleotide exchange factor activity calcium ion binding protein binding ATP binding integrin binding	No GO terms in record