MEN1 - KIT

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
MEN1	ENSG00000133895	parathyroid tumours pancreatic neuroendocrine tumour parathyroid adenoma pituitary adenoma pancreatic islet cell carcinoid	No drugs in record	four-way junction DNA binding Y-form DNA binding chromatin binding double-stranded DNA binding protein binding protein binding, bridging transcription regulatory region DNA binding protein N-terminus binding R-SMAD binding histone-lysine N-methyltransferase activity	Mnn1 (D. melanogaster)
KIT	ENSG00000157404	GIST AML TGCT mastocytosis mucosal melanoma epithelioma	CABOZANTINIB DASATINIB IMATINIB LENVATINIB PAZOPANIB PONATINIB REGORAFENIB SORAFENIB SUNITINIB	protease binding protein tyrosine kinase activity transmembrane receptor protein tyrosine kinase activity signal transducer, downstream of receptor, with protein tyrosine kinase activity stem cell factor receptor activity Ras guanyl-nucleotide exchange factor activity protein binding ATP binding cytokine binding protein homodimerization activity metal ion binding phosphatidylinositol-4,5-bisphosphate 3-kinase activity	Pvr (D. melanogaster)