KIT - PTK2

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
KIT	ENSG00000157404	GIST AML TGCT mastocytosis mucosal melanoma epithelioma	CABOZANTINIB DASATINIB IMATINIB LENVATINIB PAZOPANIB PONATINIB REGORAFENIB SORAFENIB SUNITINIB	protease binding protein tyrosine kinase activity transmembrane receptor protein tyrosine kinase activity signal transducer, downstream of receptor, with protein tyrosine kinase activity stem cell factor receptor activity Ras guanyl-nucleotide exchange factor activity protein binding ATP binding cytokine binding protein homodimerization activity metal ion binding phosphatidylinositol-4,5-bisphosphate 3-kinase activity	Pvr (D. melanogaster)
PTK2	ENSG00000169398	No diseases in record	No drugs in record	actin binding protein kinase activity protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity signal transducer activity Ras guanyl-nucleotide exchange factor activity receptor binding protein binding ATP binding JUN kinase binding protein kinase binding SH2 domain binding nucleotide binding protein serine/threonine kinase activity transferase activity kinase activity	kin-32 (C. elegans) Fak (D. melanogaster)