YWHAE - KIT

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
YWHAE	ENSG00000108953	endometrial stromal sarcoma	No drugs in record	protein binding potassium channel regulator activity enzyme binding protein domain specific binding MHC class II protein complex binding ubiquitin protein ligase binding histone deacetylase binding ion channel binding protein heterodimerization activity phosphoserine residue binding phosphoprotein binding cadherin binding involved in cell-cell adhesion	BMH1 (S. cerevisiae) BMH2 (S. cerevisiae) M117.3 (C. elegans) 14-3-3epsilon (D. melanogaster)
KIT	ENSG00000157404	GIST AML TGCT mastocytosis mucosal melanoma epithelioma	CABOZANTINIB DASATINIB IMATINIB LENVATINIB PAZOPANIB PONATINIB REGORAFENIB SORAFENIB SUNITINIB	protease binding protein tyrosine kinase activity transmembrane receptor protein tyrosine kinase activity signal transducer, downstream of receptor, with protein tyrosine kinase activity stem cell factor receptor activity Ras guanyl-nucleotide exchange factor activity protein binding ATP binding cytokine binding protein homodimerization activity metal ion binding phosphatidylinositol-4,5-bisphosphate 3-kinase activity	Pvr (D. melanogaster)