JAK3 - BUB1B

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
JAK3	ENSG00000105639	acute megakaryocytic leukaemia ETP ALL	TOFACITINIB	protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity Ras guanyl-nucleotide exchange factor activity receptor binding protein binding ATP binding protein phosphatase binding	hop (D. melanogaster)
BUB1B	ENSG00000156970	rhabdomyosarcoma	No drugs in record	protein kinase activity protein serine/threonine kinase activity protein binding ATP binding	BUB1 (S. cerevisiae) MAD3 (S. cerevisiae) bub-1 (C. elegans) Bub1 (D. melanogaster) BubR1 (D. melanogaster)