AGO1 - NOTCH1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
AGO1	ENSG00000092847	No diseases in record	No drugs in record	RNA polymerase II core promoter proximal region sequence-specific DNA binding RNA polymerase II core binding core promoter binding RNA binding double-stranded RNA binding single-stranded RNA binding protein binding miRNA binding endoribonuclease activity enzyme binding endoribonuclease activity, producing 5'-phosphomonoesters	alg-1 (C. elegans) alg-2 (C. elegans) AGO1 (D. melanogaster)
NOTCH1	ENSG00000148400	T-ALL breast bladder skin SCC lung SCC head and neck SCC	No drugs in record	core promoter binding transcriptional activator activity, RNA polymerase II transcription factor binding transcription factor activity, sequence-specific DNA binding enzyme inhibitor activity receptor activity Notch binding calcium ion binding protein binding enzyme binding chromatin DNA binding sequence-specific DNA binding protein heterodimerization activity	N (D. melanogaster)