NOTCH1 - SYK

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
NOTCH1	ENSG00000148400	T-ALL breast bladder skin SCC lung SCC head and neck SCC	No drugs in record	core promoter binding transcriptional activator activity, RNA polymerase II transcription factor binding transcription factor activity, sequence-specific DNA binding enzyme inhibitor activity receptor activity Notch binding calcium ion binding protein binding enzyme binding chromatin DNA binding sequence-specific DNA binding protein heterodimerization activity	N (D. melanogaster)
SYK	ENSG00000165025	MDS peripheral T-cell lymphoma	No drugs in record	protein kinase activity protein serine/threonine kinase activity protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity signal transducer, downstream of receptor, with protein tyrosine kinase activity integrin binding protein binding ATP binding protein kinase binding phosphatase binding Toll-like receptor binding	No GO terms in record