Genes

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Gene Ensembl ID Organism Diseases Drugs Ontology Interactions
FOSL1 ENSG00000175592 H. sapiens RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding ... 322
IRAK1 ENSG00000184216 H. sapiens protein kinase activity protein serine/threonine kinase activity NF-kappaB-inducing kinase activity ... 175
PBX1 ENSG00000185630 H. sapiens pre B-ALL myoepithelioma RNA polymerase II core promoter proximal region sequence-specific DNA binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding DNA binding ... 11
PDCD4 ENSG00000150593 H. sapiens RNA binding protein binding ... 283
PLEC ENSG00000178209 H. sapiens actin binding protein binding structural constituent of muscle ... 279
CLK2 ENSG00000176444 H. sapiens protein serine/threonine kinase activity protein serine/threonine kinase activity protein serine/threonine/tyrosine kinase activity ... 201
PRKRA ENSG00000180228 H. sapiens double-stranded RNA binding protein binding enzyme activator activity ... 148
FLNA ENSG00000196924 H. sapiens phyllodes tumour of the breast G-protein coupled receptor binding glycoprotein binding signal transducer activity ... 107
KNTC1 ENSG00000184445 H. sapiens protein binding ... 76
PLXNB2 ENSG00000196576 H. sapiens protein binding semaphorin receptor activity ... 232
NR1I2 ENSG00000144852 H. sapiens RNA polymerase II regulatory region sequence-specific DNA binding transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding steroid hormone receptor activity ... 177
JUNB ENSG00000171223 H. sapiens RNA polymerase II core promoter proximal region sequence-specific DNA binding RNA polymerase II transcription factor activity, sequence-specific DNA binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding ... 522
FLII ENSG00000177731 H. sapiens actin binding protein binding calcium ion binding ... 264
TOPORS ENSG00000197579 H. sapiens DNA binding antigen binding ubiquitin-protein transferase activity ... 406
PTPN2 ENSG00000175354 H. sapiens protein tyrosine phosphatase activity non-membrane spanning protein tyrosine phosphatase activity integrin binding ... 254
EPHB1 ENSG00000154928 H. sapiens VANDETANIB transmembrane-ephrin receptor activity protein binding ATP binding ... 204
HCLS1 ENSG00000180353 H. sapiens RNA polymerase II transcription factor binding actin binding protein binding ... 298
VPS33A ENSG00000139719 H. sapiens protein binding ... 175
IRS2 ENSG00000185950 H. sapiens signal transducer activity Ras guanyl-nucleotide exchange factor activity insulin receptor binding ... 242
CARD11 ENSG00000198286 H. sapiens DLBCL guanylate kinase activity protein binding CARD domain binding ... 331
CD28 ENSG00000178562 H. sapiens T-cell lymphoma protease binding SH3/SH2 adaptor activity protein binding ... 209
CIITA ENSG00000179583 H. sapiens PMBL Hodgkin lymphoma transcription coactivator activity protein binding ATP binding ... 202
DDIT3 ENSG00000175197 H. sapiens liposarcoma transcription regulatory region sequence-specific DNA binding RNA polymerase II core promoter proximal region sequence-specific DNA binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding ... 567
ERG ENSG00000157554 H. sapiens Ewing sarcoma prostate AML RNA polymerase II transcription factor activity, sequence-specific DNA binding DNA binding chromatin binding ... 196
ETV4 ENSG00000175832 H. sapiens Ewing sarcoma prostate carcinoma RNA polymerase II core promoter proximal region sequence-specific DNA binding RNA polymerase II transcription factor activity, sequence-specific DNA binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding ... 310
EWSR1 ENSG00000182944 H. sapiens Ewing sarcoma desmoplastic small round cell tumour ALL clear cell sarcoma sarcoma myoepithelioma mesothelioma nucleotide binding RNA binding protein binding ... 216
FANCF ENSG00000183161 H. sapiens AML leukaemia molecular_function protein binding ubiquitin protein ligase activity ... 208
GRIN2A ENSG00000183454 H. sapiens melanoma colorectal carcinoma gastric carcinoma lung carcinoma ACAMPROSATE AMANTADINE DEXTROMETHORPHAN FELBAMATE KETAMINE MEMANTINE ORPHENADRINE NMDA glutamate receptor activity Ras guanyl-nucleotide exchange factor activity extracellular-glutamate-gated ion channel activity ... 124
MALT1 ENSG00000172175 H. sapiens MALT protease binding cysteine-type endopeptidase activity ubiquitin-protein transferase activity ... 320
NACA ENSG00000196531 H. sapiens NHL DNA binding ... 219