SMAD4

ENSG00000141646 - H. sapiens

Pathways

Go term Description
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000987 core promoter proximal region sequence-specific DNA binding
GO:0001076 transcription factor activity, RNA polymerase II transcription factor binding
GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0001085 RNA polymerase II transcription factor binding
GO:0003682 chromatin binding
GO:0005515 protein binding
GO:0005518 collagen binding
GO:0030616 transforming growth factor beta receptor, common-partner cytoplasmic mediator activity
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0044212 transcription regulatory region DNA binding
GO:0046872 metal ion binding
GO:0046982 protein heterodimerization activity
GO:0070411 I-SMAD binding
GO:0070412 R-SMAD binding
GO:0000988 transcription factor activity, protein binding
GO:0003677 DNA binding
GO:0003700 transcription factor activity, sequence-specific DNA binding
GO:0043565 sequence-specific DNA binding

Drugs

No drugs in record

Diseases

Disease Name
colorectal
pancreatic
small intestine
gastrointestinal polyp

Orthologs

Gene Organism
Med D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000141646 SMAD4 ENSG00000147274 RBMX H. sapiens SDL Slorth 0.917685 View
ENSG00000094916 CBX5 ENSG00000141646 SMAD4 H. sapiens SSL Slorth 0.917571 View
ENSG00000107854 TNKS2 ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.917329 View
ENSG00000141646 SMAD4 ENSG00000173801 JUP H. sapiens SSL Slorth 0.917296 View
ENSG00000106299 WASL ENSG00000141646 SMAD4 H. sapiens SSL Slorth 0.91728 View
ENSG00000141646 SMAD4 ENSG00000151923 TIAL1 H. sapiens SSL Slorth 0.917274 View
ENSG00000141646 SMAD4 ENSG00000166797 FAM96A H. sapiens SDL Slorth 0.91726 View
ENSG00000066135 KDM4A ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.917208 View
ENSG00000076201 PTPN23 ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.917037 View
ENSG00000112062 MAPK14 ENSG00000141646 SMAD4 H. sapiens SSL Slorth 0.917019 View
ENSG00000141646 SMAD4 ENSG00000197122 SRC H. sapiens SDL Slorth 0.917012 View
ENSG00000089159 PXN ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.916844 View
ENSG00000141646 SMAD4 ENSG00000166974 MAPRE2 H. sapiens SSL Slorth 0.91681 View
ENSG00000125971 DYNLRB1 ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.91679 View
ENSG00000141646 SMAD4 ENSG00000196576 PLXNB2 H. sapiens SDL Slorth 0.916683 View
ENSG00000141646 SMAD4 ENSG00000169439 SDC2 H. sapiens SDL Slorth 0.916463 View
ENSG00000141646 SMAD4 ENSG00000160949 TONSL H. sapiens SSL Slorth 0.916408 View
ENSG00000141646 SMAD4 ENSG00000160208 RRP1B H. sapiens SSL Slorth 0.916391 View
ENSG00000092621 PHGDH ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.916379 View
ENSG00000141646 SMAD4 ENSG00000186716 BCR H. sapiens SDL Slorth 0.916347 View
ENSG00000141556 TBCD ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.916336 View
ENSG00000141646 SMAD4 ENSG00000166925 TSC22D4 H. sapiens SDL Slorth 0.916056 View
ENSG00000113575 PPP2CA ENSG00000141646 SMAD4 H. sapiens SSL Slorth 0.916039 View
ENSG00000139687 RB1 ENSG00000141646 SMAD4 H. sapiens SSL Slorth 0.91577 View
ENSG00000108840 HDAC5 ENSG00000141646 SMAD4 H. sapiens SSL Slorth 0.915769 View
ENSG00000075618 FSCN1 ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.915768 View
ENSG00000079134 THOC1 ENSG00000141646 SMAD4 H. sapiens SSL Slorth 0.915765 View
ENSG00000126858 RHOT1 ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.915688 View
ENSG00000132155 RAF1 ENSG00000141646 SMAD4 H. sapiens SSL Slorth 0.915629 View
ENSG00000141646 SMAD4 ENSG00000159251 ACTC1 H. sapiens SSL Slorth 0.915578 View
ENSG00000117450 PRDX1 ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.915455 View
ENSG00000119655 NPC2 ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.915453 View
ENSG00000141646 SMAD4 ENSG00000198625 MDM4 H. sapiens SDL Slorth 0.91545 View
ENSG00000141646 SMAD4 ENSG00000161542 PRPSAP1 H. sapiens SDL Slorth 0.915329 View
ENSG00000141646 SMAD4 ENSG00000172348 RCAN2 H. sapiens SDL Slorth 0.915258 View
ENSG00000141646 SMAD4 ENSG00000184304 PRKD1 H. sapiens SDL Slorth 0.91523 View
ENSG00000141646 SMAD4 ENSG00000158560 DYNC1I1 H. sapiens SDL Slorth 0.915223 View
ENSG00000141646 SMAD4 ENSG00000188229 TUBB4B H. sapiens SDL Slorth 0.915216 View
ENSG00000141646 SMAD4 ENSG00000187556 NANOS3 H. sapiens SDL Slorth 0.915039 View
ENSG00000100906 NFKBIA ENSG00000141646 SMAD4 H. sapiens SSL Slorth 0.91492 View