PARP1

ENSG00000143799 - H. sapiens

Pathways

Go term Description
GO:0003677 DNA binding
GO:0003910 DNA ligase (ATP) activity
GO:0003950 NAD+ ADP-ribosyltransferase activity
GO:0005515 protein binding
GO:0008134 transcription factor binding
GO:0008270 zinc ion binding
GO:0019899 enzyme binding
GO:0019901 protein kinase binding
GO:0030331 estrogen receptor binding
GO:0042802 identical protein binding
GO:0042826 histone deacetylase binding
GO:0047485 protein N-terminus binding
GO:0051287 NAD binding
GO:0070412 R-SMAD binding

Drugs

Drug name Description
OLAPARIB PARP 1, 2 & 3 inhibitor

Diseases

No diseases in record

Orthologs

Gene Organism
Parp D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000143799 PARP1 ENSG00000198265 HELZ H. sapiens SDL Slorth 0.946295 View
ENSG00000143799 PARP1 ENSG00000160752 FDPS H. sapiens SDL Slorth 0.946295 View
ENSG00000143799 PARP1 ENSG00000183955 KMT5A H. sapiens SDL Slorth 0.946201 View
ENSG00000143799 PARP1 ENSG00000162337 LRP5 H. sapiens SDL Slorth 0.946198 View
ENSG00000118260 CREB1 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.946137 View
ENSG00000143799 PARP1 ENSG00000160294 MCM3AP H. sapiens SSL Slorth 0.946135 View
ENSG00000143799 PARP1 ENSG00000174405 LIG4 H. sapiens SDL Slorth 0.946108 View
ENSG00000139842 CUL4A ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.946107 View
ENSG00000143799 PARP1 ENSG00000163161 ERCC3 H. sapiens SSL Slorth 0.946016 View
ENSG00000143799 PARP1 ENSG00000168385 SEPT2 H. sapiens SSL Slorth 0.945968 View
ENSG00000143799 PARP1 ENSG00000150593 PDCD4 H. sapiens SSL Slorth 0.945893 View
ENSG00000143799 PARP1 ENSG00000198911 SREBF2 H. sapiens SSL Slorth 0.94589 View
ENSG00000143799 PARP1 ENSG00000177733 HNRNPA0 H. sapiens SSL Slorth 0.945864 View
ENSG00000143799 PARP1 ENSG00000197879 MYO1C H. sapiens SSL Slorth 0.945618 View
ENSG00000119541 VPS4B ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.945568 View
ENSG00000143799 PARP1 ENSG00000187608 ISG15 H. sapiens SSL Slorth 0.94528 View
ENSG00000143799 PARP1 ENSG00000183337 BCOR H. sapiens SSL Slorth 0.945186 View
ENSG00000134371 CDC73 ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.94518 View
ENSG00000143799 PARP1 ENSG00000160867 FGFR4 H. sapiens SDL Slorth 0.945051 View
ENSG00000112234 FBXL4 ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.945013 View
ENSG00000143799 PARP1 ENSG00000162409 PRKAA2 H. sapiens SSL Slorth 0.944922 View
ENSG00000143799 PARP1 ENSG00000188603 CLN3 H. sapiens SSL Slorth 0.944778 View
ENSG00000111875 ASF1A ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.944739 View
ENSG00000143799 PARP1 ENSG00000169756 LIMS1 H. sapiens SDL Slorth 0.944671 View
ENSG00000143799 PARP1 ENSG00000196305 IARS H. sapiens SSL Slorth 0.944656 View
ENSG00000105568 PPP2R1A ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.944595 View
ENSG00000143799 PARP1 ENSG00000204120 GIGYF2 H. sapiens SDL Slorth 0.944539 View
ENSG00000143799 PARP1 ENSG00000183207 RUVBL2 H. sapiens SSL Slorth 0.944512 View
ENSG00000143799 PARP1 ENSG00000164885 CDK5 H. sapiens SDL Slorth 0.944482 View
ENSG00000116604 MEF2D ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.944263 View
ENSG00000143799 PARP1 ENSG00000152104 PTPN14 H. sapiens SSL Slorth 0.944245 View
ENSG00000105568 PPP2R1A ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.944024 View
ENSG00000143799 PARP1 ENSG00000169016 E2F6 H. sapiens SDL Slorth 0.944016 View
ENSG00000133794 ARNTL ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.943968 View
ENSG00000082898 XPO1 ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.943929 View
ENSG00000143799 PARP1 ENSG00000175832 ETV4 H. sapiens SSL Slorth 0.943914 View
ENSG00000118515 SGK1 ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.943903 View
ENSG00000136238 RAC1 ENSG00000143799 PARP1 H. sapiens SSL Slorth 0.943902 View
ENSG00000143799 PARP1 ENSG00000147274 RBMX H. sapiens SDL Slorth 0.943898 View
ENSG00000143799 PARP1 ENSG00000162613 FUBP1 H. sapiens SSL Slorth 0.943842 View